Still many experts say the body of research does not support the current health concerns being expressed about titanium dioxide.

Understanding Gravimetric Analysis

With its storied history and distinct properties, lithopone remains a subject of historical significance and contemporary relevance. While its applications and popularity have evolved, its role in the annals of pigment history is indisputable.

Thermogravimetric analysis (TGA) was conducted in a sample of vitaminB2@P25TiO₂NPs using a TA-THA Q5000 equipment. Temperature ramp rate: 10 °C/min, maximum temperature: 1000 °C, under air. Part of the same sample was mounted on conductive copper tape grids and observed through a Carl Zeiss Sigma scanning electron microscope (SEM) with an EDS probe, at the “Laboratorio de Microscopía y Análisis por Rayos X” (LAMARX) of National University of Córdoba (Argentina).

The main concern with nanoparticles is that they are so tiny that they are absorbed into the skin more than we want them (ideally sunscreen should remain on the surface of the skin). Once absorbed they might form unwanted complexes with proteins and they might promote the formation of evil free radicals. But do not panic, these are concerns under investigation. A 2009 review article about the safety of nanoparticles summarizes this, to date, in-vivo and in-vitro studies have not demonstrated percutaneous penetration of nanosized particles in titanium dioxide and zinc oxide sunscreens. The English translation is, so far it looks like sunscreens with nanoparticles do stay on the surface of the skin where they should be.  

Par ailleurs, dès lors que l'on recherche une certain transparence dans les travaux artistiques, son pouvoir opacifiant et son pouvoir dégradant des couleurs pas trop élevés le désignent pour remplacer le dioxyde de titane trop opaque et trop dégradant (§ Des Liants et des couleurs aux éditions EREC)

It should also be considered that due to the low pH in the stomach, the increased dissolution of the TiO₂ particles may increase its bioavailability and may facilitate the entry of titanium ions into the blood circulation. Despite the relatively large consumption of TiO₂ as a food additive, no studies on the effect of pH on its absorption and bioavailability have been found in the literature. This can be attributed to a general belief that TiO₂is completely insoluble. However, this is not completely true, as TiO₂ particles show a certain degree of solubility.

Lomon, one of the leading titanium dioxide manufacturers in China, produces the R996 grade titanium dioxide with purity levels exceeding 99%. This high purity ensures that the pigment provides excellent hiding power and color retention in paints, making it a popular choice for the paint industry.

Food additive or carcinogen? The growing list of chemicals banned in EU but used in US, by Mikaela Conley, The Guardian, June 23, 2022